DannyHolland

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So far DannyHolland has created 50 blog entries.

Community Engagement and Training Core Co-Director Presents at Puerto Rico INBRE

2023-04-20T15:18:02-05:00April 20th, 2023|

Mississippi INBRE (MS-INBRE) Community Engagement and Training Core (CETC) Co-Director Dr. Jennifer Lemacks presented at the 2023 Puerto Rico INBRE (PR-INBRE) Annual Retreat, held on March 19, 2023, to discuss CETC operations to strengthen community-engaged health disparities research in Mississippi. Her presentation, titled “Multi-Stakeholder Engagement to Support Health Disparities Research in Mississippi,” demonstrated the unique [...]

Catalysis – Enzyme Active Site

2023-03-20T13:21:40-05:00March 13th, 2023|

Enzyme kinetics is a challenging concept for students to visualize. Substrate binding to the active site of an enzyme involves multiple weak interactions between the R-groups of the amino acids and the substrate. These weak interactions increase the binding energy, lower the energy of activation, and prevents side reactions. The mechanism used by enzymes to [...]

Statistics for Epidemiology

2023-03-21T13:33:44-05:00March 13th, 2023|

In this twelve-part series, students will use an assortment of statistical tools and methods to analyze data from public databases or their own data from other projects. Each lesson is one hour long so that students can either complete one each week for a semester or multiple in a single day if preferred. The lessons [...]

Machine-Learning in Biomedical Sciences

2023-03-20T13:20:57-05:00March 13th, 2023|

Students will learn popular AI/Machine Learning (ML) methods and data science skills through hands-on projects using open-source analytical tools and pre-processed real-world public datasets. There are three single-session classroom activities, which can be used standalone or as a series. These activities are designed in three levels. Activity levels 1 and 2 focus on the most [...]

Intro to R

2023-03-20T13:20:35-05:00March 13th, 2023|

R is one of the most commonly used programming languages in the biological sciences. In this module, students will use the ggplot package with R studio to visualize biological data with no past coding experience needed. Learning Objectives Students will download R Studio and the ggplot package on a local computer. Students will learn to [...]

Computation of Omics Data

2023-03-21T13:34:40-05:00March 13th, 2023|

Magnolia supercomputer powers research at University of Southern Mississippi - high-performance computing news analysis. insideHPC. (2017, September 1). https://insidehpc.com/2017/09/magnolia-supercomputer-powers-research-university-southern-mississippi/ ‘Omics (genomics, proteomics, transcriptomics, etc.) are among the fastest changing sciences and are increasingly important to virtually every discipline in biology. Understanding what ‘omics data is and how it is used is becoming necessary for a [...]

Bactograph

2023-03-21T13:29:47-05:00March 13th, 2023|

Optogenetics uses light sensitive proteins to modify expression and behavior of cells by exposing the cells to light within a specific wavelength. Using this technique, students will create photographs with light sensitive bacteria that will produce pigments in response to light! Learning Objectives Students will be able to use photosensitive cells to produce a photograph.

Bacterial Art

2023-03-21T13:30:27-05:00March 13th, 2023|

Students will use genetically engineered bacteria producing fluorescent pigments to create art on agar plates. Painting with bacteria requires the strict use of aseptic techniques, understanding of bacterial growth rates and conditions that influence bacterial growth.  Learning Objectives Students will learn to use aseptic techniques. Students will learn about bacterial growth requirements.

Fluorescence & Organic Chemistry

2023-03-21T11:19:40-05:00March 13th, 2023|

Fluorescent pigments have revolutionized how biologists visualize structures and processes within cells. Understanding how these pigments are used is a critical skill for biologists hoping to work at the cellular level. In this module, students will generate transgenic cells that express fluorescent proteins. Learning Objectives Students will learn to create fluorescent protein expressing cells.

CRISPR

2023-03-21T10:33:35-05:00March 13th, 2023|

CRISPR has quickly become one the most important and widely used tools in genetic engineering, thanks in large part to its ease of use and low cost. In this module, students will use CRISPR to modify the expression of LacZ to create an easily recognizable phenotype in bacteria colonies.  Learning Objectives Students will use CRISPR [...]

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