Mentor Database

Researcher & Institution:Research Focus:Contact Information:
Wellington Ayensu, PhD
Jackson State University
Research focuses on psychoneuroimmunology with areas of environmental health related to public health issues, and developmental issues affecting the neonate.wellington.k.ayensu@jsums.edu
Office: (601) 979-1452
Dr. Ayensu's Faculty Page
Jason Azoulay, PhD
The University of Southern Mississippi
Research focuses on homogeneous and heterogeneous catalysis: synthesis, behavior and performance, kinetics and mechanisms, new functionality, controlled polymerization reactions, catalysts composites. Electronic, photonic, and magnetic materials: synthesis molecules and self-assembly, fundamental atomic and molecular level mechanisms, structure-function-property relationships, device fabrication and engineering. Keywords:jason.azoulay@usm.edu
Office: (601) 266-6896
Dr. Azoulay's Research Page
Fengwei Bai, PhD
The University of Southern Mississippi
Research focuses on virology and immunology.fengwei.bai@usm.edu
Office: (601) 266-4748
Dr. Bai's Faculty Page
Hamed Benghuzzi, PhD
University of Mississippi Medical Center
Research focuses on the development and applications of novel drug delivery systems.hbenghuzzi@umc.edu
David Brown, PhD
University of Mississippi Medical Center
Research focuses on employing the techniques of molecular genetics to generate stable cell lines that over express normal or in vitro mutagenized H1 variants.dbrown@umc.edu
Office: (601) 984-1849
Dr. Brown's Faculty Page
Matthew Brown, PhD
Mississippi State University
Research focuses on genomics and bioinformatics.mbrown@biology.msstate.edu
Office: (662) 325-2406
Dr. Brown's Faculty Page
Joseph Cameron, PhD
Jackson State University
Research focuses on biochemical mechanisms of toxicity and hormone action, hormonal control of mammary gland development and function, influence of diet on atherosclerosis, arteriosclerosis and fat deposition during pregnancy and lactation, and mechanisms of hypertension.joseph.a.cameron@jsums.edu
Office: (601) 979-2470
Dr. Cameron's Research Page
Denise C. Cornelius, PhD
University of Mississippi Medical Center
Dr. Cornelius’s laboratory has research focus in two major areas. The first is related to understanding how immune system activation mechanistically promotes the pathogenesis of hypertension and intrauterine growth restriction during pregnancy. Using multiple experimental models of preeclampsia, Dr. Cornelius’s lab investigates the renal and vascular mechanisms during preeclampsia and how they are influenced by inflammatory and cytotoxic immune cells and mediators. The second is related to understanding mechanisms that lead to the development of multi-organ injury during sepsis. Patients with sepsis have increased platelet activation are prone to develop multi-organ failure and have poor clinical outcomes. Dr. Cornelius’s laboratory uses a modified cecal ligation and puncture model that mimics characteristics of sepsis to investigate an important role for activated platelets in the development of multi-organ injury in sepsis. Keywords: Sepsis, Preeclampsia, Immunologydcornelius@umc.edu
Office: (601) 815-1551
Dr. Cornelius's Faculty Page
Stephen Curran, PhD
The University of Southern Mississippi
Research focuses on taxonomy, systematics, biogeography and evolution is Digeneans.stephen.curran@usm.edu
Office: (228) 872-4237
Dr. Curran's Faculty Page
Lainy Day, PhD
University of Mississippi
Research focuses on understanding the evolution, function and neuroendocrinology of brain regions involved in spatial and motor learning, principally the hippocampus and cerebellum. Projects revolve around steroid induced neuroplasticity and neurogenesis in the avian brain with some work in non-avian vertebrate models as well. Keywords: Spatial ability, neuroscience, cognition, behavior, neurobiology, endocrinology, neurogenesis, neuroplasticity, birds, avian, psychology, behavioral neuroscience, hormones, hippocampus, cerebellum, motorlainyday@olemiss.edu
Office: (662) 915-5444
Dr. Day's Faculty Page
Heather Drummond, PhD
University of Mississippi Medical Center
Research focuses on identifying proteins that form mechanosensitive ion channels in sensory neurons and vascular smooth muscle, understanding how mechanosensitive channels transduce force, and seeing how these channels are affected by disease states such as hypertension.hdrummond@umc.edu
Office: (601) 984-1812
Dr. Drummond's Faculty Page
Janet Donaldson, PhD
The University of Southern Mississippi
Research focuses on Listeria monocytogenes, a very dangerous food-borne pathogen with a high mortality rate. This lab is working to develop novel therapies that are non-antibiotic.Janet.Donaldson@usm.edu
Office: (601) 266-4748
Dr. Donaldson's Faculty Page
W. Neil Duggar, PhD
University of Mississippi Medical Center
Dr. Duggar research interests are in clinically applied research in the field of Radiation Oncology. This may include the handling of CT, MRI, PET, or other patient imaging as well as the harvesting of dosimetric data from patient treatment plans treated with external beam radiation therapy, Gamma Knife, or even High-Dose Rate Brachytherapy. Huge interest lies in the application of big data, artificial intelligence, and machine learning technologies to further clinical quality at the University of MS Medical Center, though this is a developing infrastructure. Keywords: Radiation Oncology, Machine Learning, DICOM, Radiosurgerywduggar@umc.edu
Office: (601) 815-6246
Roy Duhe, PhD
University of Mississippi Medical Center
Research focuses on identifying proteins that form mechanosensitive ion channels in sensory neurons and vascular smooth muscle, understanding how mechanosensitive channels transduce force, and seeing how these channels are affected by disease states such as hypertension.rduhe@umc.edu
Office: (601) 984-1625
Dr. Duhe's Faculty Page
Mohamed Elasri, PhD
The University of Southern Mississippi
Research focuses on global gene regulation of virulence in Staphylococcus aureus.mohamed.elasri@usm.edu
Office: (601) 266-4748
Dr. Elasri's Faculty Page
Lir-Wan Fan, PhD
University of Mississippi Medical Center
Research focused on investigating the long-term adverse effects of perinatal brain inflammation on late-onset neurodegenerative diseases, such as idiopathic Parkinson’s disease. Studies: Perinatal hypoxic‐ischemia, Periventricular leukomalacia, Intrauterine growth restriction, Parkinson’s disease, Inflammatory and neuropathic pain, Sleep disturbances. Keywords: Neurotoxicity; Development, Inflammation, Cytokines, Neonate, Hypoxic‐ischemia, Neurodegenerative diseases, Neuronal behavior, Brain damage, Spinal cord injury, Motor dysfunction, Cognitive deficits, Inflammatory and neuropathic pain.lwfan@umc.edu
Office: (601) 984-2345
Nick Fitzkee, PhD
Mississippi State University
Research focuses on understanding the relationship between a protein’s flexibility and its function, and in particular how proteins can use structural disorder to their advantage during catalysis. An additional research focus is understanding protein structure on nanoparticle surfaces. Keywords: NMR biophysics protein biochemistry kinetics surface interactions nfitzkee@chemistry.msstate.edu
Office: (662) 325-1288
Dr. Fitzkee's Faculty Page
Alex Flynt, PhD
The University of Southern Mississippi
Research broadly focuses on the role of RNA biology in post-transcriptional gene regulation. Current projects are focused on the biogenesis and function of non-coding, small regulatory RNAs.alex.flynt@usm.edu
Office: (601) 266-4748
Dr. Flynt's Faculty Page
Kevin Freeman, PhD
University of Mississippi Medical Center
Research focuses on investigation of the determinants of drug choice over non-drug alternatives and interventions for decreasing drug choice. The study of drugs as punishers with the aim of developing abuse-deterrent technologies for prescription medications. The study of interactions between obesity/eating disorders and drug abuse.kfreeman@umc.edu
Michael Garrett, PhD
University of Mississippi Medical Center
Research focuses on understanding the genetic basis of complex diseases, including kidney disease, hypertension and diabetes.mrgarrett@umc.edu
Office: (601) 984-4309
Dr. Garrett's Faculty Page
Christian Gomez, PhD
University of Mississippi Medical Center
Research focuses on hypoxia-regulated genes in carcinogenesis and prognosis, immunotherapy for cancer, and the effects of advanced age on inflammation, immunoregulation and injury.crgomez@umc.edu
Donna M. Gordon, PhD
Mississippi State University
Research focuses on characterizing the cellular response(s) induced in S. cerevisiae and Candida spp exposed to the antifungal, occidiofungin with the goal of understanding how this compound induces apoptosis at the molecular level. Specific areas of interest include: characterizing the impact of the antifungal on morphogenic switching; mapping the link between occidiofungin exposure, alterations in actin organization, and cell death; identification of fungal mutants with altered sensitivity to occidiofungin activity; determining the efficacy of occidiofungin in combinatorial drug studies. Keywords: Antimicrobial compound, yeast, microbiology, cell biologygordon@biology.msstate.edu
Office: (662) 325-9337
Dr. Gordon's Faculty Page
Bernadette Grayson, PhD
University of Mississippi Medical Center
Research focuses on central and peripheral control of obesity and diabetes using rodent models. Research also focuses on the hormonal and dietary effects of maternal in utero environment on the transmission of metabolic disease to offspring.bgrayson@umc.edu
Office: (601) 984-3809
Dr. Grayson's Faculty Page
YanLin Guo, PhD
The University of Southern Mississippi
Research focuses on the study of molecular mechanisms by which endothelial cells assemble into blood vessels and the roles of p38 MAP kinases in the regulation of endothelial cell physiology and vascular biology.yanlin.guo@usm.edu
Office: (601) 266-4748
Dr. Guo's Faculty Page
Nathan Hammer, PhD
University of Mississippi
When molecules interact noncovalently through hydrogen bonding or other electrostatic interactions, pi-pi interactions, or Van der Waals forces, their physical properties change. We study the physical properties of interacting molecules in environments ranging from the single molecule to the bulk using different laser-based spectroscopic methods and computational modeling. Our spectroscopic capabilities include high resolution Raman spectroscopy, the study of size-selected clusters in the gas phase, the use of single molecule techniques such as surface enhanced Raman spectroscopy, and other laser-based spectroscopies to study interacting molecular architectures. These include excited state lifetime, time correlated single photon counting (TCSPC) studies, ns, ps, and fs transient absorption spectroscopy, and quantum yield determinations. Such studies help answer long-standing questions involving the effects of intermolecular interactions on biologically relevant systems and also in developing devices such as solar cells that incorporate conjugated organic molecules. Both as team members and individually, we work to make new strides in the overall understanding of how molecules interact with each other and how their structure affects their resulting properties. Keywords: Raman spectroscopy, Fluorescence spectroscopy, Computational Chemistrynhammer@olemiss.edu
Office: (662) 915-3989
Dr. Hammer's Faculty Page
Dr. Hammer's Lab Page
Renita Horton, PhD
Mississippi State University
Research focuses on better characterizing the mechanisms that lead to the onset and progression of heart disease. My group is especially interested in the role of microenvironmental cues such as substrate stiffness, mechanotransduction, and biomolecules in cardiac tissue health. My second area of interest lies in enhancing our current understanding of the mechanisms that trigger sickle cell disease related co-morbidities.rhorton@abe.msstate.edu
Office: (662) 325-7345
Dr. Horton's Faculty Page
Amol Janorkar, PhD
University of Mississippi Medical Center
With his training and experience in the field of biomaterials and tissue engineering over the past 19 years, Dr. Amol Janorkar leads a research group that focuses on cell-biomaterial interactions to direct cell morphology and ultimate cell function. The Janorkar Lab uses chemical and physical modification of biopolymer substrates to create three-dimensional in vitro tissue models that achieve enhanced survival and biological function versus conventional cultures for liver, adipose, and bone tissue engineering. With his research funded by the NIH, NSF, and USDA, Dr. Janorkar has published 27 journal articles and 27 conference proceedings, and made 44 conference presentations in the past 5 years. Recognizing these research accomplishments the University of Mississippi Medical Center has awarded Dr. Janorkar the Gold, Silver, and Bronze Medallions for Research Excellence. Dr. Janorkar serves as the Director of the summer research program that has trained 140+ dental and undergraduate students over past 11 years. Recognizing his contributions to dental research, he has been inducted into the Omicron Kappa Upsilon National Dental Honor Society, which rarely inducts non-dentist faculty members. Dr. Janorkar has supervised graduate (6), undergraduate (32), dental and medical (10), and post-docs (2). His students have won 32 awards for outstanding research at local and national levels. Recognizing his teaching and mentoring, Dr. Janorkar was awarded the TEACH (Toward Educational Advancement in Care and Health) Prize, the highest award given to an educator by the University of Mississippi Medical Center. He has also been inducted into the Nelson Order of Teaching Excellence. Keywords: Tissue engineering, Drug delivery, Polymeric biomaterialsajanorkar@umc.edu
Office: (601) 984-6170
Dr. Janorhar's Faculty Page
Barbara Kaplan, PhD
Mississippi State University
Research focus is to elucidate the mechanisms by which cannabinoid compounds (i.e., those derived from marijuana) alter immune function. Interested in characterizing the mechanisms by which plant-derived compounds alter T cell function and examining the role of CB1 and CB2 in cannabinoid-mediated suppression of B cell function. Two different model systems are being utilized for these studies. The first model is a mouse-adapted influenza strain, A/PR8/34. The second model is the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS).bkaplan@cvm.msstate.edu
Office: (662) 325-1113
Dr. Kaplan's Faculty Page
Shahid Karim, PhD
The University of Southern Mississippi
Research focuses on the arthropod vectors of deadly infectious disease agents and attempts to use functional genomics tools to identify tick-derived proteins required for prolonged blood-feeding and pathogen infection in the mammalian host. Keywords: RNA interference, Genomics, proteomics, transcriptomics, recombinant protein expression, vaccine, Alpha-Gal Syndrome, Lyme Disease, Rickettsiosis, ticks, Acarishahid.karim@usm.edu
Office: (601) 266-4748
Dr. Karim's Faculty Page
Babette LaMarca, PhD
University of Mississippi Medical Center
Research focuses on identifying immune mechanisms that cause hypertension during pregnancy.bblamarca@umc.edu
Office: (601) 815-1430
Dr. LaMarca's Faculty Page
Dmitri Mavrodi, PhD
The University of Southern Mississippi
Research focuses on the functional role of natural antibiotics. Mavrodi is a molecular microbiologist who is interested in the ecology of antibiotic-producing and plant-associated bacteria.dmitri.mavrodi@usm.edu
Office: (601) 266-4748
Dr. Mavrodi's Faculty Page
Jose Javier Miguel-Hidalgo, PhD
University of Mississippi Medical Center
Research focuses on the neurobiology of alcoholism with an especial emphasis on the role of glial cells in the vulnerability and maintenance of alcohol dependence. This research uses animal models of alcohol preference and human postmortem tissue and applies immunohistochemical, biochemical and pharmacological methods to the study of changes in morphology, cell proliferation and the expression of proteins related with crucial functions mediated by glia such as glutamate transport.JMiguel-Hidalgo@umc.edu
Office: (601) 984-5791
Dr. Miguel-Hidalgo's Faculty Page
Michael Nadorff, PhD
Mississippi State University
Dr. Nadorff studies the association between sleep problems, particularly insomnia and nightmares, and suicidal behavior across the lifespan. He also has current grant funding to implement youth suicide prevention programs across the state and is interested in validating the effectiveness of these programs. Keywords: Nightmares, suicide, insomnia, youth, older adults, psychologymn487@msstate.edu
Office: (662) 325-1222
Dr. Nadorff's Faculty Page
Ifedayo Victor Ogungbe, PhD
Jackson State University
Research focuses: Medicinal Chemistry and Natural Products Drug Discovery Keywords: Protozoans, Trypanosomiasis, Natural Products, Drug Design, Drug Discovery, Medicinal Chemistry, Alphavirusifedayo.v.ogungbe@jsums.edu
Office: (601) 979-3719
Dr. Ogungbe's Faculty Page
Donna Platt, PhD
University of Mississippi Medical Center
Drug and alcohol addiction, behavioral pharmacology, pharmacogenetics Keywords: Substance abuse, addiction, alcohol, rat, monkeyDPlatt@umc.edu
Office: (601) 984-5896
Radhika Pochampall, PhD
University of Mississippi Medical Center
Research focusses on studying cellular communication between cancer stem cells and normal stem cells in breast and bone cancers.rpochampally@umc.edu
Office: (601) 815-6832
Lauren Priddy, PhD
Mississippi State University
My research focuses on developing improved biomaterial and biological treatments for bone injury and disease. In particular, we’re studying alternative antimicrobial therapies for combating Staph infection in bone, and we’re using 3D printing and design to create customized biomedical implants for applications such as bone fixation after traumatic injury.lbpriddy@abe.msstate.edu
Office: (662) 325-5988
Dr. Priddy's Faculty Page
Vijay Rangachari, PhD
The University of Southern Mississippi
Research focuses on protein-protein and protein-ligand interactions and molecular recognition, specifically delineating the underlying molecular mechanisms that dictate protein aggregation and amyloid formation. Research also focuses on developing structure-bases design of ‘conformation-specific’ molecules that are directed towards recognizing pathogenic ‘cross-beta sheet’ polypeptide structures.vijay.rangachari@usm.edu
Office: (601) 266-6044
Dr. Rangachari's Lab Page
Drazen Raucher, PhD
University of Mississippi Medical Center
Research focuses on developing an approach that allows peptide therapeutics to be delievered specifically to the tumor site.draucher@umc.edu
Office: (601) 984-1510
Dr. Raucher's Faculty Page
Jane Reckelhoff, PhD
University of Mississippi Medical Center
Research focuses on postmenopausal hypertension, polycystic ovary syndrome, and sex steroids and renal injuries. Interested in studying the mechanisms of hypertension and increasing blood pressure to determine treatments for such conditions. Keywords: Women’s health, kidney, blood pressure, androgensjreckelhoff@umc.edu
Office: (601) 984-1502
Dr. Reckelhoff's Faculty Page
James Shaffery, PhD
University of Mississippi Medical Center
My area of research is focused upon the role that rapid eye movement sleep appears to play in brain development. We aim at understanding the changes initiated when sleep, especially rapid eye movement (REM) sleep, is suppressed in early life that lead to negative outcomes later in life. Additionally, recently my research interests have expanded to investigate the role of gamma aminobutyric acid (type A) (GABAA) receptor modulators (benzodiazepine-like compounds) with high affinities for specific GABAA receptor subtypes in producing and regulating more naturalistic sleep profiles compared to those currently in medical usage. Keywords: REM sleep, electrophysiology, EEG, benzodiazepine, GABA receptors, brain developmentjshaffery@umc.edu
Office: (601) 984-6684
Dr. Shaffery's Faculty Page
C. LaShan Simpson, PhD
Mississippi State University
Research focuses on cardiovascular disease, target therapies (cell and gene therapies) and nanotechnology to treat cardiovascular disease.clsimpson@abe.msstate.edu
Office: (662) 325-8279
Dr. Simpson's Faculty Page
Andrew Smith, PhD
University of Mississippi Medical Center
Research focuses on development and testing of new imaging biomarkers for detection and staging of cancer, chronic liver disease, stroke, and osteoporosis. These are clinical and/or translational research projects that are run through the Department of Radiology. The projects often involve patient images and data and are aimed at development of new tools for use in clinical practice.asmith4@umc.edu
Dr. Smith's Faculty Page
Stanley Smith, PhD
University of Mississippi Medical Center
Research focuses on understanding disease models and mechanisms, characterization of biomarkers for human illness, prevention of adverse drug response, disparities in health treatment and outcomes, and drug metabolism and pharmakinetics.svsmith@umc.edu
Office: (601) 815-1268
Dr. Smith's Faculty Page
Frank Spradley, PhD
University of Mississippi Medical Center
Dr. Frank T. Spradley is an assistant professor of surgery and physiology. His research program focuses on assessing mechanisms whereby obesity, a global health burden, increases the risk for cardiovascular and metabolic diseases including hypertension and fatty liver injury. Hypertension is the number 1 risk factor for cardiovascular-related morbidity and mortality. Obesity reaches to impact blood pressure regulation pregnancy. His lab is currently examining how obesity impacts blood pressure regulation during pregnancy. His research interests have expanded to explore how obesity increases the risk for liver ischemia/reperfusion injury during transplantation. Keywords: Blood pressure, hypertension, pregnancy, women’s health, liver, transplantationfspradley@umc.edu
Office: (601) 815-3114
Dr. Spradley's Faculty Page
Stephen Stray, PhD
University of Mississippi Medical Center
Research focuses on virus evolution, using influenza virus as a model, and developing virus-based therapeutics for the treatment of cancer Keywords: influenza, virus evolution, cancer therapy, protein purification, virus assemblysstray@umc.edu
Office: (601) 984-1735
Dr. Stray's Faculty Page
Gopinath Subramanian, PhD
The University of Southern Mississippi
Research focuses on computational materials science, molecular dynamics and accelerated molecular dynamics, condensed matter physics, physics based modeling, and high performance computing.gopinath.subramanian@usm.edu
Justin Thornton, PhD
Mississippi State University
Research focuses on both sides of the host-pathogen interaction by characterizing how the innate immune response functions to limit progression of Streptococcus pneumoniae (pneumococcus) infections and also how virulence mechanisms of the pneumococcus enable it to cause disease. The overall goal of our research is to identify new targets for intervention which will help to decrease the morbidity and mortality associated with this pathogen.thornton@biology.msstate.edu
Office: (662) 325-8020
Dr. Thornton's Faculty Page
Michelle Tucci, PhD
University of Mississippi Medical Center
mtucci@umc.edu
Jorge E. Vidal, PhD
University of Mississippi Medical Center
Molecular pathogenesis of Streptococcus pneumoniae (pneumococcus). Mechanism(s) of colonization of the upper airways. Molecular epidemiology of pneumococcal disease. Acquisition of antibiotic resistance. Keywords: Bacterial infections, pneumococcal disease, bacterial pathogenesis, bacterial genetics, antibiotic resistance, vaccinesjvidal@umc.edu
Office: (601) 815-1236
Dr. Vidal's Lab Page
Dr. Vidal's Faculty Page
Parminder Vig, PhD
University of Mississippi Medical Center
For the past several years, the major focus of the lab was to understand the molecular mechansims of nerve cell degeneration in dominantly inherited cerebellar ataxias in order to develop treatment strategies for human patients with SCA1 or other ataxias. The current studies are looking at alterations in glia-neuron crosstalk and to determine if abnormal interactions between Bergmann glia and Purkinje cells affect Purkinje cell differentiation and function in the cerebellum. Students joining the lab learn different techniques from basic histology, immunohistochemistry and protein biochemistry to molecular biology methodologies like RT-PCR and gene-array analysis. Both in vitro cell lines and slice cultures and in vivo mouse models are being used. Based on the knowledge gained using in vitro and in vivo models of SCA1, in collaboration with Drs. Raucher and Bidwell novel elastin-like polypeptide (ELP) based therapeutic peptides (TPs) have been designed and being tested. Currently, we are optimizing the slice culture models to study the pathologic mechanisms in traumatic brain injury and multiple sclerosis.pvig@umc.edu
Office: (601) 984-5513
Dr. Vig's Faculty Page
Kedra Wallace, PhD
University of Mississippi Medical Center
Research focuses on the role of T cells in contributing to the breakdown of the blood brain barrier in women with hypertensive pregnancies. Our lab studies both the acute affects and the long-term consequences of BBB damage during pregnancy.The gynecology section of our laboratory examines the relationship between hypertension and uterine fibroid smooth muscle cell proliferation. We also examine how women’s health conditions such as uterine fibroids and endometriosis affect quality of life, depression and anxiety among women with these disorders. Keywords: Women’s health, hypertension, mental health, neuroscience, obstetrics, gynecologykwallace2@umc.edu
Office: 601-984-5396
Ian Webb, PhD
University of Mississippi Medical Center
Research focuses to understand the mechanisms underlying diurnal rhythms in drug reward and their influences on the development and expression of drug addiction. Currently using a DREADD approach to examine the effects of mPFC glutamatergic neuron inhibition on daily rhythms in psychostimulant-induced CPP and self-administration.iwebb@umc.edu
Mark Welch, PhD
Mississippi State University
Research focuses on how natural populations respond to changes in their environment. A major focus of his lab is to identify molecular mechanisms that increase phenotypic variation by altering gene expression. To do this, he preforms functional genomic analysis on variable, natural populations of sunflowers.mw497@msstate.edu
Office: (662) 325-7564
Dr. Welch's Lab Page
Thomas Werfel, PhD
University of Mississippi
Our lab employs an interdisciplinary approach lying at the interface of materials chemistry, bioengineering, and the biological sciences to discover and implement next-generation cancer therapies. We design environmentally-responsive drug delivery systems to improve the therapeutic index of existing drugs or generate novel drugs against previously “undruggable” targets. We develop therapies that target specific genes or proteins crucial to cancer cell growth to precisely assail cancerous tissue while sparing healthy tissue. And we elucidate cellular and molecular processes that impact a) drug delivery efficiency and b) cancer progression, resistance to therapy, and metastasis. Keywords: Nanotechnology, Cancer, Immunotherapy, Metastasis, Drug Delivery, Bioengineeringtawerfel@olemiss.edu
Office: 662-915-8969
Dr. Werfel's Faculty Page
Jan Williams, PhD
University of Mississippi Medical Center
Research focuses on renal physiology and diabetes and hypertension-induced nephropathy.JMWilliams5@umc.edu
Office: (601) 984-1634
Dr. William's Faculty Page
Lakiesha Williams, PhD
Mississippi State University
Research focuses on biomechanics of tissues and organs.lwilliams@abe.msstate.edu
Office: (662) 325-0205
Dr. William's Faculty Page
Hao Xu, PhD
The University of Southern Mississippi
The Xu lab has three major research focuses: 1) We are interested in understanding specific protein-protein interactions and protein-lipid interactions that lead to membrane fusion, which is required for intracellular traffic, hormone secretion and neurotransmission. To achieve that, we exploit a multifaceted approach which includes biochemical analysis, biophysical measurements and in vitro reconstitution. 2) We are interested in unraveling the regulation of mast cell degranulation, which is the culprit of allergic inflammation. We exploit cell-based secretion assays developed in the Xu lab to interrogate the function of specific proteins in the release of different mast cell mediators, from histamine to TNF. We routinely use RNAi to knock down gene expression or CRISPR technology to knock out a target gene. Our goal is to establish functional assays for proteins that are potential drug targets for the control of allergic inflammation. 3) We are interested in host-viral interactions that play central roles in the survival/propagation of Kaposi’s sarcoma-associated herpesvirus in host cells. At the moment, we are investigating the biochemical and functional relationship between SNAREs and previously overlooked tegument proteins. This line of investigation is conducted in collaboration with colleagues in other universities Keywords: Membrane fusion; secretion; protein traffic; mast cell degranulation; allergy; host-viral interactionhao.xu@usm.edu
Office: (601) 266-4748
Dr. Xu's Faculty Page
Shan Yang, PhD
Jackson State University
My research interests focus on the development of optical systems, and in turn, the application of novel optical system to address problems in biological and medical system. Keywords: Raman spectroscopy, Full field of view Raman imaging, dental caries detection, water probing and analysis in biological tissues, skin hydrationShan.Yang@jsums.edu
Office: (601) 979-3611
Dr. Yang's Lab Page
Clement Yedjou, PhD
Jackson State University
Research focuses on pharmacology, toxicology and therapeutics.clement.yedjou@jsums.edu
Office: (601) 979-0215
Dr. Yedjou's Faculty Page
Xinchun Zhou, PhD
University of Mississippi Medical Center
Research focuses on exploring lipid markers in diagnosis and prognosis of cancers, as well as on the metabolic pathways of identified lipid biomarkers.xzhou@umc.edu